Tuesday, July 31, 2007

More noise!

Since the last post was on how noise was good for some genes, it seems suitable to say that noise is, of course, bad for others:

http://www.nature.com/ng/journal/v39/n8/full/ng2071.html

Says that essential genes cluster in low-nucleosome areas due to the decrease in noise that such a cluster will cause. Basically, since misexpression of said genes will cause severe phenotypes, they are clustered in places where misexpression is less likely to happen randomly, even for a short time -- hence less noise. Kind of an interesting result. I like the idea that noise in gene expression is caused by chromatin remodelling. It's clever.

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